While many on the left are reveling in the downfall of South Carolina Gov. Mark Sanford after he disclosed his affair with a woman in Argentina, there's a sympathetic figure being overlooked that might have the necessary background to fill the void left by the governor should he resign.

On CNBC's June 30 "The Kudlow Report," Wall Street Journal senior economics writer Steve Moore explained his close relationship with the Sanfords and raised a new political possibility.

"This is such a tough thing for me Larry, because as you know Mark Sanford has been a long-time friend of mine," Moore said. "This story truly breaks my heart." Moore suggested that South Carolina First Lady Jenny Sanford run for her husband's seat - as he called her "the brains of the operation."