The set-up is the show's star and producer Larry David is taking some medication that is making him urinate quite forcefully.
It's so powerful that while urinating in his assistant's bathroom, he accidentally splashed some of it on a picture of Jesus Christ hanging on a nearby wall.
This prompted the following response from Donohue (video embedded below the fold h/t Big Hollywood):
At one point in the show, David goes to the bathroom in a Catholic home and splatters urine on a picture of Jesus; he doesn't clean it off. Then a Catholic woman goes to the bathroom, sees the picture and concludes that Jesus is crying. She then summons her equally stupid mother and the two of them fall to their knees in prayer. When David and Jerry Seinfeld (playing himself) are asked if they ever experienced a miracle, David answers, "every erection is a miracle." That's what passes for creativity these days.
Was Larry David always this crude? Would he think it comedic if someone urinated on a picture of his mother? This might be fun to watch, but since HBO only likes to dump on Catholics (it was just a couple of weeks ago that Sarah Silverman insulted Catholics on "Real Time with Bill Maher"), and David is Jewish, we'll never know.
A Big Hollywood reader sent an e-mail message to the website asking an interesting question:
Of course, the hypocrisy is that Mr. David would never exhibit such gross contempt for any other religion, especially Islam. Can you imagine the s**t storm that would follow if David pissed on a painting of the prophet Muhammad? Of course, HBO, the complicit scum that they are, would not have allowed that to air.
No, likely not.